podcast image for This Week in Startups
This Week in Startups
Description

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Episodes
  • 2025 / 3 / 11
    The Future of AI Customer Support with LiveX AI’s Jia Li | AI Basics with Google Cloud

    In this episode of AI Basics, Jason sits down with Jia Li from LiveX AI to explore how human-like AI agents are changing the game for businesses. Instead of clunky bots, these AI agents engage customers in...

  • 2025 / 3 / 11
    Student Roy Lee Hacks Amazon, SBF's Jailhouse Chat + more! | E2095

    Timestamps:(0:00) Roy Lee's hack and Amazon's reaction(3:03) MicroStrategy's Bitcoin strategy(4:29) Market reactions to Trump's policies(6:33) Creating value in current market conditions(8:00) South by...

  • 2025 / 3 / 7
    AI’s Next Leap: Hyper-Realistic Agents & Unlimited Power | E2094

    Today’s show: AI is evolving at lightning speed—smarter assistants, faster models, and now, the massive energy demands that come with it. In this episode, Alex dives into two cutting-edge companies from the...

  • 2025 / 3 / 5
    Coreweave IPO, AVRide & Digg is Back! | E2093

    This Week in Startups is brought to you by…Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit...

  • 2025 / 3 / 4
    AI Agents & the Future of Work with LangChain’s Harrison Chase | AI Basics with Google Cloud

    In this episode: Jason sits down with Harrison Chase, CEO of LangChain, to explore how AI-powered agents are transforming the way startups operate. They discuss the shift from traditional entry-level roles to...

  • 2025 / 3 / 4
    US Crypto Reserve Bombshell, Ramp’s $13B Climb, & more | E2092

    Today’s show: Trump just floated the idea of a U.S. Crypto Reserve, suggesting a 10 bips transaction tax and naming unexpected altcoins like XRP, Solana, and Cardano. Jason and Alex break down what this means...

  • 2025 / 3 / 1
    Board Talk Empire with GRIN's Brandon Brown, Founder Hacks & SEC Memecoin Clarity? | E2091

    Today’s show: Jason and Alex break down the latest head-scratching SEC ruling on meme coins—did they just legalize pump-and-dumps to protect Trump’s token? Plus, they dive into why venture debt can destroy...

  • 2025 / 2 / 27
    The Incredible Double Interview: Superhuman and Robinhood

    This Week in Startups is brought to you by…Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistNorthwest Registered Agent. Get more privacy, more options, and more done—visit...

  • 2025 / 2 / 27
    The Incredible Double Interview: Superhuman and Robinhood | E2090

    This Week in Startups is brought to you by…Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistNorthwest Registered Agent. Get more privacy, more options, and more done—visit...

  • 2025 / 2 / 25
    Apple Drops $500B on AI while Google Gemini Eyes Your iOS Devices! | E2089

    Today’s show: Jason and Lon break down the latest trends shaping AI training, the evolving job market, and the shifting landscape of social media. A tribute to Steve Jobs on what would have been his 70th...

  • 2025 / 2 / 22
    Castelion Hypersonic Missiles and Crunchbase’s AI Powered Predictions | E2088

    This Week in Startups is brought to you by…Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTLinkedIn Jobs. Post your first job...

  • 2025 / 2 / 20
    EV Truck Startup Nikola Runs Out of Juice | E2087

    This Week in Startups is brought to you by…Gusto. Get three months free when you run your first payroll at http://gusto.com/twistLemon.io. Get 15% off your first 4 weeks of developer time at...

  • 2025 / 2 / 19
    Is $LIBRA the End of Memecoins? with Coffeezilla | E2086

    In today's episode: Jason and Alex break down one of the craziest crypto stories yet—a $100M meme coin meltdown, insider trading, and Argentina’s president caught in the middle. Coffeezilla joins the show to...

  • 2025 / 2 / 15
    IPO Shakeups, NVIDIA’s Big Bets & Must-Know Founder Hacks | E2085

    Today’s show: IPO shakeups, big AI moves, and essential founder hacks—this episode covers it all. Jason breaks down Robinhood’s 6X stock surge and his strategy for $HOOD, plus the latest on tech IPOs as Turo...

  • 2025 / 2 / 12
    Slow Ventures' Creators Fund and Helion Energy's Fusion Reactors | 2084

    This Week in Startups is brought to you by…Vanta. Get $1000 off your SOC 2 athttps://www.vanta.com/twistNorthwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get...

  • 2025 / 2 / 11
    Tech's Super Bowl, Huge Earnings Week, Lon Returns and more! | E2083

    Today on This Week in Startups: Lon Harris is back, and we’re diving into all things Super Bowl—especially the tech takeover in this year’s commercials. We break down the biggest ad moments, from Squarespace...

  • 2025 / 2 / 8
    Gas Stations in Space and Carried Interest on the Chopping Block | E2082

    This Week in Startups is brought to you by…Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain athttps://www.Squarespace.com/TWISTAtlassian. Head...

  • 2025 / 2 / 6
    Is Palantir's Surge Just Hype | E2081

    This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at...

  • 2025 / 2 / 4
    Lovable's Anton Osika on Revolutionizing Software Development and OpenAI Drops Deep Research | E2080

    OpenAI dropped Deep Research—hilariously, the exact same name as Google’s existing tool. Jason and Alex dive into the AI arms race, break down Lovable.dev’s insane growth to $10M ARR in weeks, and test...

  • 2025 / 2 / 1
    Is OpenAI Really Worth $300B? ElevenLabs’ Series C & YC’s Funding Focus | E2079

    Today’s show: The AI revolution is about to hit your household—Jason and Alex break down how general-purpose robots, AI-powered chicken coops, and voice clones are redefining daily life and work. They dig...

  • 2025 / 1 / 29
    Boom Supersonic's Milestones, OpenAI Ethics, and Startup Tools | E2078

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  • 2025 / 1 / 27
    DeepSeek Rattles Markets + SailPoint's Going Public… again? | E2077

    Today’s show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA’s market cap and forcing a rethink on AI infrastructure spending. We explore the...

  • 2025 / 1 / 24
    Twilio Bets Small, DeepSeek Scares & the GameOn Fraud | E2076

    This Week in Startups is brought to you by… Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Squarespace. TWiST listeners: use code TWIST to save 10%...

  • 2025 / 1 / 23
    Created By Humans | Sila’s Battery Evolution | E2075

    This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist Netsuite. Download the CFO's Guide to AI and Machine Learning for free at...

  • 2025 / 1 / 21
    Trump, Memecoins, and What to Expect from the New Administration | E2074

    Today’s show: Jason and Alex explore America's fascination with billionaires and self-made figures, touching on recent events in Washington, DC, and the tech industry's political influence. They discuss Gen...

  • 2025 / 1 / 17
    TikTok Ban, Data Centers in Space… and What's a Vector? | E2073

    Today’s show: Alex sits down with two CEOs from companies freshly added to the TWIST500. We get a masterclass from Bob van Luijt of Weaviate, on vector databases helping AI and LLMs do what they do. An then...

  • 2025 / 1 / 16
    What’s Going On With Google Gemini Deep Research? | E2072

    This Week in Startups is brought to you by… PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to:...

  • 2025 / 1 / 14
    Profound, Resistant AI & OpenAI’s Economic Pitch | E2071

    Today’s show: Alex covers Mark Zuckerberg’s Joe Rogan interview, OpenAI’s economic pitch and the pending IPO of India’s Groww. Our guests include two companies freshly added to the TWIST500: James Cadwallader...

  • 2025 / 1 / 10
    The LA Fire's Cost and the U.S. Jobs Report | E2070

    This Week in Startups is brought to you by… Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit...

  • 2025 / 1 / 8
    Meta's Moderation and Nvidia's Domination | E2069

    This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at...

  • 2025 / 1 / 6
    Twist News: Fusion, Rural Investment, and Applied AI | E2068

    This Week in Startups is brought to you by… PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to:...

  • 2025 / 1 / 4
    Venture Concentration, High-Skill Immigration, And Who Should Buy Lyft? | E2067

    This Week in Startups is brought to you by… Paddle. Wherever you want to take your business, go there with Paddle. Go to paddle.com/twist to get started with your exclusive listener fee-free period. Fitbod....

  • 2024 / 12 / 31
    2024 TWISTY Awards | E2066

    This Week in Startups is brought to you by… Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST OpenPhone. TWiST...

  • 2024 / 12 / 24
    Palantir’s Valuation, VC’s Go To Washington and Much More | E2065

    This Week in Startups is brought to you by… Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at ⁠⁠https://w⁠⁠⁠⁠ww.oracle.com/twist⁠⁠⁠ DevSquad. TWIST listeners can get 10% off at...

  • 2024 / 12 / 20
    Codeium’s Vision for AI-Driven Development with Varun Mohan | E2064

    This Week in Startups is brought to you by… Squarespace. Turn your idea into a new website! Go to https://www.Squarespace.com/TWIST for a free trial. When you’re ready to launch, use offer code TWIST to save...

  • 2024 / 12 / 19
    Databricks' Record Raise, TikTok goes to the Supreme Court, and all about the Grammarly-Coda Deal | E2063

    This Week in Startups is brought to you by… Coda. Coda empowers your startup by bringing words, tables, and teams together. Strategize, plan, and track goals effectively with all your valuable data in one...

  • 2024 / 12 / 18
    Sora Disappoints, ChatGPT Pro Tested, Inference Time Reasoning & More with Sunny Madra | E2062

    Timestamps: (0:00) Jason and Sunny kick off the show (1:26) Discussing Grok's recent developments and Middle East tech inspiration (3:51) Global business challenges and Jason's 2025 announcements (7:53)...

  • 2024 / 12 / 17
    Silicon Valley Clones and Jersey Drones: Decoding the Signals with Nicole Wischoff | E2061

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  • 2024 / 12 / 13
    Cyera's Hypergrowth, Cake's Cap Table Push, and ServiceTitan's Stellar IPO | E2060

    This Week in Startups is brought to you by… LinkedIn Jobs. A business is only as strong as its people, and every hire matters. Go to https://www.linkedin.com/twist to post your first job for free. Terms and...

  • 2024 / 12 / 12
    The Top 6 Startup Finance FAQ’s | Startup Finance Basics w/ Kruze's Scott Orn

    Todays show: In the latest edition of Startup Finance Basics, Jason sits down with Scott Orn from Kruze Consulting to answer the six most important founder/startup questions around finance, accounting, and...

  • 2024 / 12 / 12
    Negative Venture Returns, GM Kneecaps Cruise, and Finix joins the TWiST500 | E2059

    This Week in Startups is brought to you by… OpenPhone. Create business phone numbers for you and your team that work through an app on your smartphone or desktop. TWiST listeners can get an extra 20% off any...

  • 2024 / 12 / 11
    Drones, Deepfakes, and Disruptors with Lon Harris, Remento and Cuby | E2058

    This Week in Startups is brought to you by… Squarespace. Turn your idea into a new website! Go to https://www.Squarespace.com/TWIST for a free trial. When you’re ready to launch, use offer code TWIST to save...

  • 2024 / 12 / 10
    TWiST News: Bitcoin’s Future, Reddit Answers, SEC Shifts, and more! | E2057

    This Week in Startups is brought to you by… Ramp. The corporate card and spend management software designed to help you save time and money. Get $250 when you join Ramp today at...

  • 2024 / 12 / 7
    Ghost Engineers, Measuring Productivity, & Memecoin Scams | E2056

    Todays show: In this episode, we discuss Hailey Welch and the viral Hawk coin, then discuss David Sachs' new White House role and recent job data's economic impact. We address the United Healthcare CEO's...

  • 2024 / 12 / 5
    Year-End Planning for Startup Success | Startup Finance Basics w/ Kruze's Scott Orn

    Todays show: In the latest edition of Startup Finance Basics, Jason sits down with Scott Orn from Kruze Consulting to tackle essential year-end planning for startups. "Year-End Planning: Setting Your Startup...

  • 2024 / 12 / 5
    TWiST News: $100k Veteran Pitch Winner EMPEQ, US Unicorn Dominance, and T500 Updates | E2055

    This Week in Startups is brought to you by… Gusto. Gusto is easy online payroll, benefits, and HR built for modern small businesses. Get three months free when you run your first payroll at...

  • 2024 / 12 / 4
    TWiST News: Bitcoin, Saylor's Microsoft Pitch, and the Delaware-Tesla Fight | E2054

    This Week in Startups is brought to you by… OpenPhone. Create business phone numbers for you and your team that work through an app on your smartphone or desktop. TWiST listeners can get an extra 20% off any...

  • 2024 / 12 / 3
    TWiST News: Pardons, Enron, Crypto's Moment, and the Future of Chinese Venture | E2053

    This Week in Startups is brought to you by… Squarespace. Turn your idea into a new website! Go to https://www.Squarespace.com/TWIST for a free trial. When you’re ready to launch, use offer code TWIST to save...

  • 2024 / 11 / 27
    The Self-Driving Unicorn You Need to Meet & MicroStrategy's Bitcoin Bet | E2052

    Todays show: Jason and Alex welcomed Alex Kendall to the show. He's the founder and CEO of Wayve, an AI company working on self-driving. You might recall that Wayve raised $1 billion earlier this year, but...

  • 2024 / 11 / 26
    TWiST News: Startups & Wealth Taxes, The Bitcoin Boom, and The OpenAI Browser | E2051

    This Week in Startups is brought to you by… Squarespace. Turn your idea into a new website! Go to https://www.Squarespace.com/TWIST for a free trial. When you’re ready to launch, use offer code TWIST to save...