This Week in Startups - PodcastSaver

This Week in Startups

Description

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Episodes

2026 / 4 / 14

Bittensor’s (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275

This Week In Startups is made possible by:Sentry - https://sentry.io/twist Deel - https://deel.com/twist Netsuite - https://netsuite.com/twist Plaud - https://Plaud.ai/twistToday’s show:*TAO just had its...

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2026 / 4 / 11

Bittensor Drama! TAO down 15%! | E2274

This Week In Startups is made possible by:Pilot - https://pilot.com/TWISTSquarespace -https://squarespace.com/TWISTNorthwest Registered Agent - https://northwestregisteredagent.com/TWISTPlaud -...

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2026 / 4 / 9

Anthropic’s Mythos is a cyber-weapon, so you can’t have it | E2273

Anthropic just built a model so dangerous, they’re not even going to release it (for now). On TWiST, Jason, Alex, and Neurometric CEO Rob May discuss whether or not this is just another frontier model or a...

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2026 / 4 / 7

3 AI Agents That Actually Replaced Human Jobs | E2272

Anthropic just pulled the plug on Claude subscriptions for OpenClaw and every third party agentic tool. So Jason and Lon welcome back three of our top TWiST OpenClaw experts to break down what it means, how...

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2026 / 4 / 3

AI Rebuilt Every YC W26 Startup. Should Founders Be Scared? | E2271

This Week In Startups is made possible by:Deel - deel.com/twistGrasshopper Bank - grasshopper.bank/twistRender - render.com/twistPlaud - Plaud.ai/twistAn AI “holding company” rebuilt dozens of YC Winter ‘26...

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2026 / 4 / 2

How 3 CEOs Use AI to Run $10B in Companies | This Week in AI

This Week in AI, JCal sits down with three CEOs building the infrastructure, intelligence, and interfaces for the next era of AI: Jeremy Fraenkel (CEO, Fundamental), Victor Riparbelli (CEO, Synthesia), and...

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2026 / 4 / 1

Venture Roundtable: SpaceX IPO, AI's PR Crisis, and the Defense Tech Bubble | E2270

This Week In Startups is made possible by:PaperOS - https://PaperOS.com/twistNorthwest Registered Agent- https://northwestregisteredagent.com/twistEvery.io - https://Every.ioPlaud -...

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2026 / 3 / 31

The 5-Step Framework for AI Agents That Improve While You Sleep | E2269

This Week In Startups is made possible by:Quo - https://quo.com/TWiSTLinkedIn Jobs - https://LinkedIn.com/twistIru - https://iru.com/twistPlaud - https://Plaud.ai/twistToday’s show:Google project manager...

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2026 / 3 / 27

The $60 billion resource hiding in space, and the start trying to mine it (feat. Matt Gialich, Astroforge) | E2268

This Week In Startups is made possible by:Wispr Flow - https://wisprflow.ai/twistCircle - http://circle.so/twistDeel - http://deel.com/twistToday’s show:AstroForge is building low-cost, replicable spacecraft...

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2026 / 3 / 26

This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267

This Week In Startups is made possible by:Luma AI - https://lumalabs.ai/twistEvery.io - https://every.ioLemon.io - https://Lemon.io/twistPlaud - https://Plaud.ai/twistToday’s show:What do drug discovery, the...

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2026 / 3 / 25

$2.5B Chip Heist, The Future of American AI, and Purpose-Built Robots | This Week in AI Ep 6

This Week in AI sneak peak! If you enjoy the episode find us on Spotify, Apple podcasts and YouTube by looking up "This Week in AI" or by going to thisweekinai.aiThis week Jason sat down with Jake...

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2026 / 3 / 24

Compliance Startup Scandal... Is Delve Guilty? | E2266

This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twistLinkedIn Jobs - https://linkedIn.com/twistSentry - https://sentry.io/twistPlaud -...

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2026 / 3 / 20

The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265

This Week In Startups is made possible by:Northwest Registered Agent - https://www.northwestregisteredagent.com/twistCircle - https://circle.so/twistNetsuite - https://www.netsuite.com/twistToday’s...

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2026 / 3 / 18

How Robinhood became a $68B company w/ Vlad Tenev

This Week In Startups is made possible by:Deel - https://deel.com/twistLinkedIn Jobs - https://LinkedIn.com/twist.Iru - https://iru.com/twistToday’s show:We’ve got a treat for you today on TWiST! Jason is...

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2026 / 3 / 16

Are Brain-Computer Interfaces Actually Ready for Humans?

This Week In Startups is made possible by:Caldera + Lab - https://CalderaLab.com/TWISTNorthwest Registered Agent - https://northwestregisteredagent.com/twistLemon - https://Lemon.io/twistToday’s...

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2026 / 3 / 14

One Genius Rule That Made This Coffee Brand Famous | EP 2262

Legendary British ad man Rory Sutherland invented a fake business on a podcast, a coffee shop appealing to the busy commuter called “Flat White or F**k Off.”But it’s one thing to have a post go big on TikTok...

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2026 / 3 / 11

The Global Expansion of Self-Driving Vehicles

This Week In Startups is made possible by:Circle - http://circle.so/twistSentry - http://Sentry.ioDeel - http://deel.com/twistPlaud - http://Plaud.ai/twistToday’s show:It’s self-driving time! We’re going deep...

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2026 / 3 / 10

How agents will change banking forever | E2260

This Week In Startups is made possible by:Northwest Registered Agent - ⁠⁠northwestregisteredagent.com/twist⁠⁠Quo - ⁠⁠quo.com/TWiST⁠⁠Gusto - ⁠⁠Gusto.com/twist⁠⁠Plaud - http://Plaud.ai/twistAthena -...

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2026 / 3 / 6

Wisdom of the $TAO: the future is decentralized AI

This Week In Startups is made possible by:Every Banking - https://Every.iohttps://Lemon.io - Lemon.io/twistWispr Flow - https://wisprflow.ai/twistPlaud - https://plaud.ai/twistRo.co -...

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2026 / 3 / 5

Is Anthropic Making the Biggest Mistake in AI History | E2258

This Week In Startups is made possible by:LinkedIn Jobs - https://LinkedIn.com/twist.Deel - https://deel.com/twistIru - https://iru.com/twist!Today’s show:It’s a packed TWiST Today! WITH US, we’ve got Erik...

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2026 / 3 / 3

How the OpenClaw foundation bullet-proofed its future (w/Dave Morin) | E2257

This Week In Startups is made possible by:Circle — http://circle.so/twistHubspot Creators — http://clickhubspot.com/twist2Uber AI Solutions — http://uber.com/ai-solutionsToday’s show: *Dave Morin joined the...

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2026 / 2 / 28

The Biggest Private Funding Round in History | E2256

This Week In Startups is made possible by:Deel - http://deel.com/twistWispr Flow - https://wisprflow.ai/twistLuma AI - https://lumalabs.ai/twistToday’s show:*$110 billion buys you 15% of OpenAI. Amazon,...

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2026 / 2 / 26

Behind the Scenes with an early OpenClaw contributor! | E2252

This Week In Startups is made possible by:Lemon IO - https://Lemon.io/twistEvery.io - https://every.io Sentry.io- https://sentry.io/twistToday’s show:We’re going behind the curtain today — it’s a packed...

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2026 / 2 / 24

Kill Your Startup’s Knowledge Chaos with OpenClaw (with Oliver Henry and Jeff Weisbein) | E2254

This Week In Startups is made possible by:Caldera Lab - [calderalab.com/twist](https://calderalab.com/twist)Iru - [iru.com](http://Iru.com)LinkedIn Jobs - http://linkedin.com/twist*OpenClaw is incredible at...

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2026 / 2 / 21

We Asked 3 Experts How to Get More Value out of OpenClaw | E2253

This Week In Startups is made possible by:Gusto - https://Gusto.com/twistCircle - https://circle.so/twistNorthwest Registered Agent - https://northwestregisteredagent.com/twistToday’s show:*Getting OpenClaw...

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2026 / 2 / 19

When Will Openclaw go Mainstream? | E2252

This Week In Startups is made possible by:Gusto - Try Gusto today and get 3 months free at http://uber.com/ai-solutionsCrusoe Cloud - Reserve your capacity for the latest GPU’s at...

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2026 / 2 / 17

Will OpenAI Tank OpenClaw? | E2251

Will OpenAI Tank OpenClaw? | E2251This Week In Startups is made possible by:Northwest Registered Agent - https://www.northwestregisteredagent.com/twistLemon IO - https://lemon.io/twistLinkedIn Jobs -...

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2026 / 2 / 14

OpenClaw is Our Friend Now | E2250

This Week In Startups is made possible by:Sentry - http://sentry.io/twistCircle - http://Circle.so/twistWispr Flow - https://wisprflow.ai/twistToday’s show: What makes OpenClaw feel so much more ALIVE than...

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2026 / 2 / 12

Why J-Cal Invested to 200K in a former Employee | E2249

This Week In Startups is made possible by:NetSuite - https://www.netsuite.com/twistLuma AI - https://lumalabs.ai/twistSquarespace - https://squarespace.com/twistToday’s show: On today’s epsiode of TWiST,...

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2026 / 2 / 12

How These 3 Founders are building on Open Claw | E2248

This Week In Startups is made possible by:Hubspot - http://clickhubspot.com/twist2Deel - http://deel.com/twistIru - http://www.iru.com/Today’s show: Today on TWiST we’re joined by 3 founders building on Open...

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2026 / 2 / 10

Does Clawdbot (OpenClaw) Need Eyes? (feat. Alex Finn and Matt Van Horn) | E2247

This Week In Startups is made possible by:LinkedIn - http://linkedin.com/twistEvery.io - http://every.io/Northwest registered Agent - www.northwestregisteredagent.com/twistToday’s show: Sean Liu gave his...

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2026 / 2 / 7

We built OpenClaw Ultron to replace 20 people at our company | E2246

This Week In Startups is made possible by:Crusoe Cloud - https://crusoe.ai/savingsLemon IO - https://Lemon.io/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistThanks to our...

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2026 / 2 / 4

Savvy is HQ Trivia + Wordle (feat. Scott Rogowsky) | E2245

This Week In Startups is made possible by:Circle - http://Circle.so/twistCaldera Lab - http://calderalab.com/TWISTLinkedIn - http://linkedin.com/twistToday’s show: There was a time, not long ago, when offices...

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2026 / 2 / 3

Where early-stage founders MUST focus to success | E2244

This Week In Startups is made possible by:Quadratic - http://quadratic.ai/twistToday’s show: Don’t get distracted! Here are the MOST CRUCIAL aspects of running a startup, where founders need to keep their...

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2026 / 2 / 3

SpaceX + xAI deal gets us one step closer to Musk Industries | E2243

This Week In Startups is made possible by:Uber - http://uber.com/twistDeel - http://deel.com/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistToday’s show: SpaceX is buying xAI,...

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2026 / 1 / 31

How OpenClaw (Clawdbot) Is Rewriting the Way Our Team Works with Rahul Sood | E2242

This Week In Startups is made possible by:Deel - http://deel.com/twistLinkedIn Jobs - http://linkedin.com/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistToday’s show: On...

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2026 / 1 / 31

AI Bots Take Over | E2242

This Week In Startups is made possible by:Deel - http://deel.com/twistLinkedIn Jobs - http://linkedin.com/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistToday’s show: On...

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2026 / 1 / 29

How decriminalization led to an explosion in cannabis startups (Feat. Ford Smith, Andrew Duffy, and Socrates Rosenfeld) | E2241

This Week In Startups is made possible by:Gusto - http://Gusto.com/twistZite - http://zite.com/twistCircle.so - http://circle.so/twistGuest links: Andrew Duffy, Founder and CEO, http://sparkplug.app — Retail...

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2026 / 1 / 27

Clawdbot is an inflection point in AI history | E2240

This Week In Startups is made possible by:Quo - http://quo.com/TWiSTLemon IO - https://lemon.io/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistToday’s show: Jason is back from...

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2026 / 1 / 24

Why You’ll Choose an AI Doctor (feat. Fred Almeida and Max Weiss) | E2239

This Week In Startups is made possible by:Sentry.io - sentry.io/twistHubspot - clickhubspot.com/twist2Northwest Registered Agent - https://northwestregisteredagent.com/twistToday’s show:One day soon, you...

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2026 / 1 / 21

From Blood Transfusions to Burritos, How Zipline is Automating Delivery | E2238

This Week In Startups is made possible by:Northwest Registered Agent - www.northwestregisteredagent.com/twistCrusoe Cloud - https://crusoe.ai/savingsLinkedIn Jobs - http://linkedIn.com/twistToday’s show: On...

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2026 / 1 / 20

How startups suddenly became “cool” in Japan (feat. Shin Takamiya of Globis Capital) | E2237

This Week In Startups is made possible by:Circle.so - http://Circle.so/twistDeel - http://deel.com/twistUber AI Solutions - http://uber.com/twistToday’s show:Not long ago, promising young Japanese graduates...

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2026 / 1 / 16

Avoiding buzzwords and marketing-speak (feat. Thomas McInerney) | E2236

This Week In Startups is made possible by:Lemon.io - https://lemon.io/twistDeel - http://deel.com/twistLinkedIn Jobs - http://linkedIn.com/twistToday’s show: Some pitches sound just like ads… and it’s a huge...

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2026 / 1 / 14

Japan’s Startup Revolution (feat. Kathy Matsui) | E2235

This Week In Startups is made possible by:Every.io - http://every.io/LinkedIn Jobs - https://www.linkedin.com/twistZite - http://zite.com/twistToday’s show: Why do 40% of Japanese students want to build a...

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2026 / 1 / 13

How to Make Billions from Exposing Fraud | E2234

This Week In Startups is made possible by:Netsuite - https://www.netsuite.com/twistLumaAi - https://lumalabs.ai/twistSquarespace - https://squarespace.com/twistToday’s show: Government fraud and waste has...

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2026 / 1 / 13

Secrets of Startup Recruiting in the US AND Japan! (feat. Sho Takei) | E2233

This Week In Startups is made possible by:Northwest Registered Agent - www.northwestregisteredagent.com/twistCaldera Lab - http://calderalab.com/TWISTPipedrive - http://pipedrive.com/twistToday’s show: TWiST...

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2026 / 1 / 10

Jason’s Top CES Products and Takeaways | E2232

This Week In Startups is made possible by:Hubspot - http://clickhubspot.com/twist1Circle.so - http://circle.so/twistSentry - http://sentry.io/twistToday’s show: On the last TWiST episode before Jason goes to...

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2026 / 1 / 8

AI makes you more creative, AI Roundtable with Steven Johnson and Grant Lee | E2231

This Week In Startups is made possible by:Gusto - https://www.gusto.com/twistLemon IO - https://lemon.io/twistQuo - http://quo.com/TWiSTToday’s show: We keep hearing about how AI is killing our ability to...

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2026 / 1 / 6

2026 Starts with a bang: META AI Drama and Nvidia’s $20B Groq Acquisition | E2230

This Week In Startups is made possible by:Crusoe Cloud - https://crusoe.ai/buildUber - http://uber.com/twistEvery.io - http://every.io/Today’s show: Jason and Alex are BACK on TWiST for 2026! This holiday...

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2025 / 12 / 30

THE 2025 TWISTY AWARDS! Biggest Trends, Best Guests, Top Name Drops, and more | E2229

This Week In Startups is made possible by:LinkedIn Ads - http://linkedin.com/thisweekinstartupsSquarespace -https://squarespace.com/twistHubspot - http://clickhubspot.com/twist1Today’s show: We’re saying...

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