Description
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the worldâs greatest founders, operators, investors, and innovators.
Episodes
- 2026 / 6 / 3The Startup Turning Space Into a Logistics NetworkThis Week In Startups is made possible by:Northwest Registered Agent - NorthwestRegistereAagent.com/TWISTEvery - Every.ioSentry - Sentry.io/TWISTTodayâs show:Want to get to space? Several launch companies can...
- 2026 / 6 / 3The project SpaceX's first employee raised $500M forThis Week In Startups is made possible by:Northwest Registered Agent - NorthwestRegistereAagent.com/TWISTEvery - Every.ioSentry - Sentry.io/TWISTTodayâs show:Want to get to space? Several launch companies can...
- 2026 / 6 / 1This Startup Fused Human Brain Cells with Silicon Chips | E2295This Week In Startups is made possible by:Deel https://deel.com/twistQuo https://quo.com/TWiSTLinkedIn Jobs https://LinkedIn.com/twistTodayâs show:Cortical Labs is the worldâs first company selling biological...
- 2026 / 5 / 29How to Raise a Seed Round in 2026: Ask Jason | E2294This Week In Startups is made possible by:partner 1 - linkpartner 2 - linkpartner 3 - linkTodayâs show:Jason breaks down the real math behind raising a seed round. Hereâs the funnel: contact 150 firms, get 50...
- 2026 / 5 / 27The Drone Company Quietly Taking Over DeliveryThis Week In Startups is made possible by:Render - render.com/twistDeel - deel.com/twistNorthwest Registered Agent - northwestregisteredagent.com/twistTodayâs show:The "Ryanair of drone delivery"...
- 2026 / 5 / 23From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E2292This Week In Startups is made possible by:Every.io https://every.ioShopify https://shopify.com/twistRender https://render.com/twistPlaud https://Plaud.ai/twistTodayâs show:Startups like Divergent Technologies...
- 2026 / 5 / 20Avi Patel on the startup that copied Kled and why he called out General Catalyst by name | E2291This Week In Startups is made possible by:Grasshopper Bank - https://grasshopper.bank/twistLinkedIn - https://linkedIn.com/twistNorthwest Registered Agent - https://northwestregisteredagent.com/twistPlaud -...
- 2026 / 5 / 18Why does Gen Z hate AI?This Week In Startups is made possible by:Vanta - Vanta.com/TWISTSentry - Sentry.io/TWISTDeel - Deel.com/TWISTTodayâs show:AI is the villain of the 2026 commencement cycle, with business luminaries â...
- 2026 / 5 / 18Why is Gen Z hates AI?This Week In Startups is made possible by:Vanta - Vanta.com/TWISTSentry - Sentry.io/TWISTDeel - Deel.com/TWISTTodayâs show:AI is the villain of the 2026 commencement cycle, with business luminaries â...
- 2026 / 5 / 15The Self-Driving Startup Nobody Saw Coming | E2289This Week In Startups is made possible by:IM8 Health: IM8health.com/TWISTSquarespace: Squarespace.com/TWISTRender - Render.com/TWISTSelf-driving just stopped being a science problem and became an engineering...
- 2026 / 5 / 13How Many Startups Will Survive OpenAI? | E2288This Week In Startups is made possible by:Pilot -â https://Pilot.com/TWISTâ Grasshopper Bank -â https://Grasshopper.bank/TWISTâ Quo -â https://Quo.com/TWiSTâ Plaud - â https://Plaud.ai/twistâ Anthropic just...
- 2026 / 5 / 13How the 1% Will Own Compute (and What It Means for You)The future of AI isn't a smarter chatbot. It's a model that watches your screen, listens to the room, and acts on what it sees. We dug into Thinking Machines' new interaction model, what it means...
- 2026 / 5 / 11Cerebras's IPO goes vertical, and the death of OpenClaw? | E2287Todayâs show:Cerebras just jacked its IPO range to $150â$160 a share, OpenAI bought a consulting firm to seed its $4 billion private-equity joint venture, and a startup in Oakland is electrolyzing magnesium...
- 2026 / 5 / 95,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286This Week In Startups is made possible by:IM8 Health - https://IM8health.com/TWISTEvery - Every.ioSentry - https://Sentry.io/TWISTBanks donât want to hand over their data to AI labs. So David Moscatelli built...
- 2026 / 5 / 6The end of Venture Capital? (VC Roundtable) | E2285This Week In Startups is made possible by:Grasshopper Bank - https://grasshopper.bank/twistPaperOS - https://paperos.com/twistLinkedIn Jobs - https://linkedIn.com/twistPlaud - https://Plaud.ai/twistThe top 5...
- 2026 / 5 / 5Naval's GP, Ankur Nagpal, Breaks Down The Viral âUSVCâ Fund | E2284This Week In Startups is made possible by:Render - render.com/twistVanta - vanta.com/twistNorthwest Registered Agent - northwestregisteredagent.com/twistHave you wanted to invest in venture capital alongside...
- 2026 / 5 / 1Can an AI Agent Legally Own a Company? Christian van der Henst's Wild Experiment| E2283This Week In Startups is made possible by:Pilot - https://pilot.com/twistShopify - https://shopify.com/twistGrasshopper Bank - https://grasshopper.bank/twistTodayâs show:An AI agent named Valerie is running a...
- 2026 / 4 / 30Mastering AI Video Marketing w/ Magnific CEO JoaquĂn Cuenca Abela | AI BasicsThe TWiST AI Basics series is made possible by Google Cloud!Check out Google Cloudâs new report, âFuture of AI: Perspectives on generative media for startups,â Featuring thoughts from todayâs guest, JoaquĂn...
- 2026 / 4 / 29The $10M+ Bet on a Beanie That Reads Your Brain | Sabi & the Future of BCI | E2282This Week In Startups is made possible by:Render - https://Render.com/TWISTNorthwest Registered Agent - https://NorthwestRegisteredAgent.com/TWISTLinkedIn Jobs - https://LinkedIn.com/TWISTTodayâs show:A...
- 2026 / 4 / 28To the left of this of thumbnail i want to add a chinese flag to the left destroying the meta logo. because the title is China Kills Meta / Manus Deal (Story Of The Year) | E2281This Week In Startups is made possible by:IM8 Health - IM8health.com/twistSentry - Sentry.io/twistDeel - Deel.com/twistPlaud - https://Plaud.ai/twistWhatâs the technology story of the year? No, itâs not...
- 2026 / 4 / 28China Kills Meta / Manus Deal (Story Of The Year) | E2281This Week In Startups is made possible by:IM8 Health - IM8health.com/twistSentry - Sentry.io/twistDeel - Deel.com/twistPlaud - https://Plaud.ai/twistWhatâs the technology story of the year? No, itâs not...
- 2026 / 4 / 25Navalâs $500 VC fund, the Maduro Polymarket scandal, and NYT defends theft and murder | E2280This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twist LinkedIn Jobs - https://LinkedIn.com/twistTodayâs show:Itâs a News and Off-Duty weekend...
- 2026 / 4 / 25The Defense Tech Startup YC Kicked Out of a Meeting is Now Arming America | E2280This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twist Render - https://render.com/twist Agree - https://agree.com Ro - https://Ro.co/Twist Plaud -...
- 2026 / 4 / 22SpaceX and Cursor team up to topple Claude Code | E2279This Week In Startups is made possible by:LinkedIn Jobs - linkedIn.com/twistGrasshopper Bank - grasshopper.bank/twistNotion - notion.comTodayâs show:This week, SpaceX announced that it was partnering with AI...
- 2026 / 4 / 21Why Your Company Should Own Its AI Model | E2278This Week In Startups is made possible by:Quo - https://quo.com/TWiST Vanta - https://vanta.com/twist Pilot - https://pilot.com/twist Plaud - https://Plaud.ai/twistTodayâs show:*Eragon CEO Josh Sirota...
- 2026 / 4 / 183D-Printed Homes for $99K: ICONâs Jason Ballard on the future of housing | E2277This Week In Startups is made possible by:IM8 Health - https://IM8health.com/twist Grasshopper Bank - https://grasshopper.bank/twist Northwest Registered Agent - https://northwestregisteredagent.com/twist...
- 2026 / 4 / 15This 22-Year-Old Built TikTok for Mobile Games, and Itâs Growing Fast | E2276This Week In Startups is made possible by:LinkedIn Jobs - LinkedIn.com/twist Every.io - every.io Render - render.com/twistTodayâs show:*Imagine scrolling through mobile games the way your flip through your...
- 2026 / 4 / 14Bittensorâs (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275This Week In Startups is made possible by:Sentry - https://sentry.io/twist Deel - https://deel.com/twist Netsuite - https://netsuite.com/twist Plaud - https://Plaud.ai/twistTodayâs show:*TAO just had its...
- 2026 / 4 / 11Bittensor Drama! TAO down 15%! | E2274This Week In Startups is made possible by:Pilot - https://pilot.com/TWISTSquarespace -https://squarespace.com/TWISTNorthwest Registered Agent - https://northwestregisteredagent.com/TWISTPlaud -...
- 2026 / 4 / 9Anthropicâs Mythos is a cyber-weapon, so you canât have it | E2273Anthropic just built a model so dangerous, theyâre not even going to release it (for now). On TWiST, Jason, Alex, and Neurometric CEO Rob May discuss whether or not this is just another frontier model or a...
- 2026 / 4 / 73 AI Agents That Actually Replaced Human Jobs | E2272Anthropic just pulled the plug on Claude subscriptions for OpenClaw and every third party agentic tool. So Jason and Lon welcome back three of our top TWiST OpenClaw experts to break down what it means, how...
- 2026 / 4 / 3AI Rebuilt Every YC W26 Startup. Should Founders Be Scared? | E2271This Week In Startups is made possible by:Deel - deel.com/twistGrasshopper Bank - grasshopper.bank/twistRender - render.com/twistPlaud - Plaud.ai/twistAn AI âholding companyâ rebuilt dozens of YC Winter â26...
- 2026 / 4 / 2How 3 CEOs Use AI to Run $10B in Companies | This Week in AIThis Week in AI, JCal sits down with three CEOs building the infrastructure, intelligence, and interfaces for the next era of AI: Jeremy Fraenkel (CEO, Fundamental), Victor Riparbelli (CEO, Synthesia), and...
- 2026 / 4 / 1Venture Roundtable: SpaceX IPO, AI's PR Crisis, and the Defense Tech Bubble | E2270This Week In Startups is made possible by:PaperOS - https://PaperOS.com/twistNorthwest Registered Agent- https://northwestregisteredagent.com/twistEvery.io - https://Every.ioPlaud -...
- 2026 / 3 / 31The 5-Step Framework for AI Agents That Improve While You Sleep | E2269This Week In Startups is made possible by:Quo - https://quo.com/TWiSTLinkedIn Jobs - https://LinkedIn.com/twistIru - https://iru.com/twistPlaud - https://Plaud.ai/twistTodayâs show:Google project manager...
- 2026 / 3 / 27The $60 billion resource hiding in space, and the start trying to mine it (feat. Matt Gialich, Astroforge) | E2268This Week In Startups is made possible by:Wispr Flow - https://wisprflow.ai/twistCircle - http://circle.so/twistDeel - http://deel.com/twistTodayâs show:AstroForge is building low-cost, replicable spacecraft...
- 2026 / 3 / 26This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267This Week In Startups is made possible by:Luma AI - https://lumalabs.ai/twistEvery.io - https://every.ioLemon.io - https://Lemon.io/twistPlaud - https://Plaud.ai/twistTodayâs show:What do drug discovery, the...
- 2026 / 3 / 25$2.5B Chip Heist, The Future of American AI, and Purpose-Built Robots | This Week in AI Ep 6This Week in AI sneak peak! If you enjoy the episode find us on Spotify, Apple podcasts and YouTube by looking up "This Week in AI" or by going to thisweekinai.aiThis week Jason sat down with Jake...
- 2026 / 3 / 24Compliance Startup Scandal... Is Delve Guilty? | E2266This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twistLinkedIn Jobs - https://linkedIn.com/twistSentry - https://sentry.io/twistPlaud -...
- 2026 / 3 / 20The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265This Week In Startups is made possible by:Northwest Registered Agent - https://www.northwestregisteredagent.com/twistCircle - https://circle.so/twistNetsuite - https://www.netsuite.com/twistTodayâs...
- 2026 / 3 / 18How Robinhood became a $68B company w/ Vlad TenevThis Week In Startups is made possible by:Deel - https://deel.com/twistLinkedIn Jobs - https://LinkedIn.com/twist.Iru - https://iru.com/twistTodayâs show:Weâve got a treat for you today on TWiST! Jason is...
- 2026 / 3 / 16Are Brain-Computer Interfaces Actually Ready for Humans?This Week In Startups is made possible by:Caldera + Lab - https://CalderaLab.com/TWISTNorthwest Registered Agent - https://northwestregisteredagent.com/twistLemon - https://Lemon.io/twistTodayâs...
- 2026 / 3 / 14One Genius Rule That Made This Coffee Brand Famous | EP 2262Legendary British ad man Rory Sutherland invented a fake business on a podcast, a coffee shop appealing to the busy commuter called âFlat White or F**k Off.âBut itâs one thing to have a post go big on TikTok...
- 2026 / 3 / 11The Global Expansion of Self-Driving VehiclesThis Week In Startups is made possible by:Circle - http://circle.so/twistSentry - http://Sentry.ioDeel - http://deel.com/twistPlaud - http://Plaud.ai/twistTodayâs show:Itâs self-driving time! Weâre going deep...
- 2026 / 3 / 10How agents will change banking forever | E2260This Week In Startups is made possible by:Northwest Registered Agent - â â northwestregisteredagent.com/twistâ â Quo - â â quo.com/TWiSTâ â Gusto - â â Gusto.com/twistâ â Plaud - http://Plaud.ai/twistAthena -...
- 2026 / 3 / 6Wisdom of the $TAO: the future is decentralized AIThis Week In Startups is made possible by:Every Banking - https://Every.iohttps://Lemon.io - Lemon.io/twistWispr Flow - https://wisprflow.ai/twistPlaud - https://plaud.ai/twistRo.co -...
- 2026 / 3 / 5Is Anthropic Making the Biggest Mistake in AI History | E2258This Week In Startups is made possible by:LinkedIn Jobs - https://LinkedIn.com/twist.Deel - https://deel.com/twistIru - https://iru.com/twist!Todayâs show:Itâs a packed TWiST Today! WITH US, weâve got Erik...
- 2026 / 3 / 3How the OpenClaw foundation bullet-proofed its future (w/Dave Morin) | E2257This Week In Startups is made possible by:Circle â http://circle.so/twistHubspot Creators â http://clickhubspot.com/twist2Uber AI Solutions â http://uber.com/ai-solutionsTodayâs show: *Dave Morin joined the...
- 2026 / 2 / 28The Biggest Private Funding Round in History | E2256This Week In Startups is made possible by:Deel - http://deel.com/twistWispr Flow - https://wisprflow.ai/twistLuma AI - https://lumalabs.ai/twistTodayâs show:*$110 billion buys you 15% of OpenAI. Amazon,...
- 2026 / 2 / 26Behind the Scenes with an early OpenClaw contributor! | E2252This Week In Startups is made possible by:Lemon IO - https://Lemon.io/twistEvery.io - https://every.io Sentry.io- https://sentry.io/twistTodayâs show:Weâre going behind the curtain today â itâs a packed...