This Week in Startups - PodcastSaver

This Week in Startups

Description

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Episodes

2026 / 5 / 15

The Self-Driving Startup Nobody Saw Coming | E2289

This Week In Startups is made possible by:IM8 Health: IM8health.com/TWISTSquarespace: Squarespace.com/TWISTRender - Render.com/TWISTSelf-driving just stopped being a science problem and became an engineering...

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2026 / 5 / 13

How Many Startups Will Survive OpenAI? | E2288

This Week In Startups is made possible by:Pilot -⁠ https://Pilot.com/TWIST⁠Grasshopper Bank -⁠ https://Grasshopper.bank/TWIST⁠Quo -⁠ https://Quo.com/TWiST⁠Plaud - ⁠https://Plaud.ai/twist⁠Anthropic just...

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2026 / 5 / 11

Cerebras's IPO goes vertical, and the death of OpenClaw? | E2287

Today’s show:Cerebras just jacked its IPO range to $150–$160 a share, OpenAI bought a consulting firm to seed its $4 billion private-equity joint venture, and a startup in Oakland is electrolyzing magnesium...

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2026 / 5 / 9

5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286

This Week In Startups is made possible by:IM8 Health - https://IM8health.com/TWISTEvery - Every.ioSentry - https://Sentry.io/TWISTBanks don’t want to hand over their data to AI labs. So David Moscatelli built...

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2026 / 5 / 6

The end of Venture Capital? (VC Roundtable) | E2285

This Week In Startups is made possible by:Grasshopper Bank - https://grasshopper.bank/twistPaperOS - https://paperos.com/twistLinkedIn Jobs - https://linkedIn.com/twistPlaud - https://Plaud.ai/twistThe top 5...

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2026 / 5 / 5

Naval's GP, Ankur Nagpal, Breaks Down The Viral “USVC” Fund | E2284

This Week In Startups is made possible by:Render - render.com/twistVanta - vanta.com/twistNorthwest Registered Agent - northwestregisteredagent.com/twistHave you wanted to invest in venture capital alongside...

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2026 / 5 / 1

Can an AI Agent Legally Own a Company? Christian van der Henst's Wild Experiment| E2283

This Week In Startups is made possible by:Pilot - https://pilot.com/twistShopify - https://shopify.com/twistGrasshopper Bank - https://grasshopper.bank/twistToday’s show:An AI agent named Valerie is running a...

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2026 / 4 / 30

Mastering AI Video Marketing w/ Magnific CEO Joaquín Cuenca Abela | AI Basics

The TWiST AI Basics series is made possible by Google Cloud!Check out Google Cloud’s new report, “Future of AI: Perspectives on generative media for startups,” Featuring thoughts from today’s guest, Joaquín...

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2026 / 4 / 29

The $10M+ Bet on a Beanie That Reads Your Brain | Sabi & the Future of BCI | E2282

This Week In Startups is made possible by:Render - https://Render.com/TWISTNorthwest Registered Agent - https://NorthwestRegisteredAgent.com/TWISTLinkedIn Jobs - https://LinkedIn.com/TWISTToday’s show:A...

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2026 / 4 / 28

To the left of this of thumbnail i want to add a chinese flag to the left destroying the meta logo. because the title is China Kills Meta / Manus Deal (Story Of The Year) | E2281

This Week In Startups is made possible by:IM8 Health - IM8health.com/twistSentry - Sentry.io/twistDeel - Deel.com/twistPlaud - https://Plaud.ai/twistWhat’s the technology story of the year? No, it’s not...

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2026 / 4 / 28

China Kills Meta / Manus Deal (Story Of The Year) | E2281

This Week In Startups is made possible by:IM8 Health - IM8health.com/twistSentry - Sentry.io/twistDeel - Deel.com/twistPlaud - https://Plaud.ai/twistWhat’s the technology story of the year? No, it’s not...

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2026 / 4 / 25

Naval’s $500 VC fund, the Maduro Polymarket scandal, and NYT defends theft and murder | E2280

This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twist LinkedIn Jobs - https://LinkedIn.com/twistToday’s show:It’s a News and Off-Duty weekend...

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2026 / 4 / 25

The Defense Tech Startup YC Kicked Out of a Meeting is Now Arming America | E2280

This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twist Render - https://render.com/twist Agree - https://agree.com Ro - https://Ro.co/Twist Plaud -...

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2026 / 4 / 22

SpaceX and Cursor team up to topple Claude Code | E2279

This Week In Startups is made possible by:LinkedIn Jobs - linkedIn.com/twistGrasshopper Bank - grasshopper.bank/twistNotion - notion.comToday’s show:This week, SpaceX announced that it was partnering with AI...

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2026 / 4 / 21

Why Your Company Should Own Its AI Model | E2278

This Week In Startups is made possible by:Quo - https://quo.com/TWiST Vanta - https://vanta.com/twist Pilot - https://pilot.com/twist Plaud - https://Plaud.ai/twistToday’s show:*Eragon CEO Josh Sirota...

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2026 / 4 / 18

3D-Printed Homes for $99K: ICON’s Jason Ballard on the future of housing | E2277

This Week In Startups is made possible by:IM8 Health - https://IM8health.com/twist Grasshopper Bank - https://grasshopper.bank/twist Northwest Registered Agent - https://northwestregisteredagent.com/twist...

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2026 / 4 / 15

This 22-Year-Old Built TikTok for Mobile Games, and It’s Growing Fast | E2276

This Week In Startups is made possible by:LinkedIn Jobs - LinkedIn.com/twist Every.io - every.io Render - render.com/twistToday’s show:*Imagine scrolling through mobile games the way your flip through your...

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2026 / 4 / 14

Bittensor’s (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275

This Week In Startups is made possible by:Sentry - https://sentry.io/twist Deel - https://deel.com/twist Netsuite - https://netsuite.com/twist Plaud - https://Plaud.ai/twistToday’s show:*TAO just had its...

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2026 / 4 / 11

Bittensor Drama! TAO down 15%! | E2274

This Week In Startups is made possible by:Pilot - https://pilot.com/TWISTSquarespace -https://squarespace.com/TWISTNorthwest Registered Agent - https://northwestregisteredagent.com/TWISTPlaud -...

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2026 / 4 / 9

Anthropic’s Mythos is a cyber-weapon, so you can’t have it | E2273

Anthropic just built a model so dangerous, they’re not even going to release it (for now). On TWiST, Jason, Alex, and Neurometric CEO Rob May discuss whether or not this is just another frontier model or a...

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2026 / 4 / 7

3 AI Agents That Actually Replaced Human Jobs | E2272

Anthropic just pulled the plug on Claude subscriptions for OpenClaw and every third party agentic tool. So Jason and Lon welcome back three of our top TWiST OpenClaw experts to break down what it means, how...

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2026 / 4 / 3

AI Rebuilt Every YC W26 Startup. Should Founders Be Scared? | E2271

This Week In Startups is made possible by:Deel - deel.com/twistGrasshopper Bank - grasshopper.bank/twistRender - render.com/twistPlaud - Plaud.ai/twistAn AI “holding company” rebuilt dozens of YC Winter ‘26...

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2026 / 4 / 2

How 3 CEOs Use AI to Run $10B in Companies | This Week in AI

This Week in AI, JCal sits down with three CEOs building the infrastructure, intelligence, and interfaces for the next era of AI: Jeremy Fraenkel (CEO, Fundamental), Victor Riparbelli (CEO, Synthesia), and...

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2026 / 4 / 1

Venture Roundtable: SpaceX IPO, AI's PR Crisis, and the Defense Tech Bubble | E2270

This Week In Startups is made possible by:PaperOS - https://PaperOS.com/twistNorthwest Registered Agent- https://northwestregisteredagent.com/twistEvery.io - https://Every.ioPlaud -...

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2026 / 3 / 31

The 5-Step Framework for AI Agents That Improve While You Sleep | E2269

This Week In Startups is made possible by:Quo - https://quo.com/TWiSTLinkedIn Jobs - https://LinkedIn.com/twistIru - https://iru.com/twistPlaud - https://Plaud.ai/twistToday’s show:Google project manager...

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2026 / 3 / 27

The $60 billion resource hiding in space, and the start trying to mine it (feat. Matt Gialich, Astroforge) | E2268

This Week In Startups is made possible by:Wispr Flow - https://wisprflow.ai/twistCircle - http://circle.so/twistDeel - http://deel.com/twistToday’s show:AstroForge is building low-cost, replicable spacecraft...

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2026 / 3 / 26

This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267

This Week In Startups is made possible by:Luma AI - https://lumalabs.ai/twistEvery.io - https://every.ioLemon.io - https://Lemon.io/twistPlaud - https://Plaud.ai/twistToday’s show:What do drug discovery, the...

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2026 / 3 / 25

$2.5B Chip Heist, The Future of American AI, and Purpose-Built Robots | This Week in AI Ep 6

This Week in AI sneak peak! If you enjoy the episode find us on Spotify, Apple podcasts and YouTube by looking up "This Week in AI" or by going to thisweekinai.aiThis week Jason sat down with Jake...

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2026 / 3 / 24

Compliance Startup Scandal... Is Delve Guilty? | E2266

This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twistLinkedIn Jobs - https://linkedIn.com/twistSentry - https://sentry.io/twistPlaud -...

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2026 / 3 / 20

The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265

This Week In Startups is made possible by:Northwest Registered Agent - https://www.northwestregisteredagent.com/twistCircle - https://circle.so/twistNetsuite - https://www.netsuite.com/twistToday’s...

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2026 / 3 / 18

How Robinhood became a $68B company w/ Vlad Tenev

This Week In Startups is made possible by:Deel - https://deel.com/twistLinkedIn Jobs - https://LinkedIn.com/twist.Iru - https://iru.com/twistToday’s show:We’ve got a treat for you today on TWiST! Jason is...

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2026 / 3 / 16

Are Brain-Computer Interfaces Actually Ready for Humans?

This Week In Startups is made possible by:Caldera + Lab - https://CalderaLab.com/TWISTNorthwest Registered Agent - https://northwestregisteredagent.com/twistLemon - https://Lemon.io/twistToday’s...

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2026 / 3 / 14

One Genius Rule That Made This Coffee Brand Famous | EP 2262

Legendary British ad man Rory Sutherland invented a fake business on a podcast, a coffee shop appealing to the busy commuter called “Flat White or F**k Off.”But it’s one thing to have a post go big on TikTok...

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2026 / 3 / 11

The Global Expansion of Self-Driving Vehicles

This Week In Startups is made possible by:Circle - http://circle.so/twistSentry - http://Sentry.ioDeel - http://deel.com/twistPlaud - http://Plaud.ai/twistToday’s show:It’s self-driving time! We’re going deep...

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2026 / 3 / 10

How agents will change banking forever | E2260

This Week In Startups is made possible by:Northwest Registered Agent - ⁠⁠northwestregisteredagent.com/twist⁠⁠Quo - ⁠⁠quo.com/TWiST⁠⁠Gusto - ⁠⁠Gusto.com/twist⁠⁠Plaud - http://Plaud.ai/twistAthena -...

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2026 / 3 / 6

Wisdom of the $TAO: the future is decentralized AI

This Week In Startups is made possible by:Every Banking - https://Every.iohttps://Lemon.io - Lemon.io/twistWispr Flow - https://wisprflow.ai/twistPlaud - https://plaud.ai/twistRo.co -...

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2026 / 3 / 5

Is Anthropic Making the Biggest Mistake in AI History | E2258

This Week In Startups is made possible by:LinkedIn Jobs - https://LinkedIn.com/twist.Deel - https://deel.com/twistIru - https://iru.com/twist!Today’s show:It’s a packed TWiST Today! WITH US, we’ve got Erik...

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2026 / 3 / 3

How the OpenClaw foundation bullet-proofed its future (w/Dave Morin) | E2257

This Week In Startups is made possible by:Circle — http://circle.so/twistHubspot Creators — http://clickhubspot.com/twist2Uber AI Solutions — http://uber.com/ai-solutionsToday’s show: *Dave Morin joined the...

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2026 / 2 / 28

The Biggest Private Funding Round in History | E2256

This Week In Startups is made possible by:Deel - http://deel.com/twistWispr Flow - https://wisprflow.ai/twistLuma AI - https://lumalabs.ai/twistToday’s show:*$110 billion buys you 15% of OpenAI. Amazon,...

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2026 / 2 / 26

Behind the Scenes with an early OpenClaw contributor! | E2252

This Week In Startups is made possible by:Lemon IO - https://Lemon.io/twistEvery.io - https://every.io Sentry.io- https://sentry.io/twistToday’s show:We’re going behind the curtain today — it’s a packed...

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2026 / 2 / 24

Kill Your Startup’s Knowledge Chaos with OpenClaw (with Oliver Henry and Jeff Weisbein) | E2254

This Week In Startups is made possible by:Caldera Lab - [calderalab.com/twist](https://calderalab.com/twist)Iru - [iru.com](http://Iru.com)LinkedIn Jobs - http://linkedin.com/twist*OpenClaw is incredible at...

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2026 / 2 / 21

We Asked 3 Experts How to Get More Value out of OpenClaw | E2253

This Week In Startups is made possible by:Gusto - https://Gusto.com/twistCircle - https://circle.so/twistNorthwest Registered Agent - https://northwestregisteredagent.com/twistToday’s show:*Getting OpenClaw...

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2026 / 2 / 19

When Will Openclaw go Mainstream? | E2252

This Week In Startups is made possible by:Gusto - Try Gusto today and get 3 months free at http://uber.com/ai-solutionsCrusoe Cloud - Reserve your capacity for the latest GPU’s at...

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2026 / 2 / 17

Will OpenAI Tank OpenClaw? | E2251

Will OpenAI Tank OpenClaw? | E2251This Week In Startups is made possible by:Northwest Registered Agent - https://www.northwestregisteredagent.com/twistLemon IO - https://lemon.io/twistLinkedIn Jobs -...

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2026 / 2 / 14

OpenClaw is Our Friend Now | E2250

This Week In Startups is made possible by:Sentry - http://sentry.io/twistCircle - http://Circle.so/twistWispr Flow - https://wisprflow.ai/twistToday’s show: What makes OpenClaw feel so much more ALIVE than...

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2026 / 2 / 12

Why J-Cal Invested to 200K in a former Employee | E2249

This Week In Startups is made possible by:NetSuite - https://www.netsuite.com/twistLuma AI - https://lumalabs.ai/twistSquarespace - https://squarespace.com/twistToday’s show: On today’s epsiode of TWiST,...

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2026 / 2 / 12

How These 3 Founders are building on Open Claw | E2248

This Week In Startups is made possible by:Hubspot - http://clickhubspot.com/twist2Deel - http://deel.com/twistIru - http://www.iru.com/Today’s show: Today on TWiST we’re joined by 3 founders building on Open...

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2026 / 2 / 10

Does Clawdbot (OpenClaw) Need Eyes? (feat. Alex Finn and Matt Van Horn) | E2247

This Week In Startups is made possible by:LinkedIn - http://linkedin.com/twistEvery.io - http://every.io/Northwest registered Agent - www.northwestregisteredagent.com/twistToday’s show: Sean Liu gave his...

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2026 / 2 / 7

We built OpenClaw Ultron to replace 20 people at our company | E2246

This Week In Startups is made possible by:Crusoe Cloud - https://crusoe.ai/savingsLemon IO - https://Lemon.io/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistThanks to our...

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2026 / 2 / 4

Savvy is HQ Trivia + Wordle (feat. Scott Rogowsky) | E2245

This Week In Startups is made possible by:Circle - http://Circle.so/twistCaldera Lab - http://calderalab.com/TWISTLinkedIn - http://linkedin.com/twistToday’s show: There was a time, not long ago, when offices...

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