podcast image for This Week in Startups
This Week in Startups
Description

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world's greatest founders, operators, investors, and innovators.

Episodes
  • 2026 / 8 / 3
    How Bespoke faked AI until it actually worked (w/ Akemi Tsunagawa) | E2320

    This Week In Startups is made possible by: Odoo https://Odoo.com/twist Quo https://quo.com/TWiST Northwest Registered Agent https://northwestregisteredagent.com/twist Today's show: *Before Bespoke's "travel...

  • 2026 / 7 / 31
    Why AI has no taste and how to fix it (w/ Thais Castello Branco) | E2319

    This Week In Startups is made possible by: YSecurity https://YSecurity.io/TWIST MongoDB https://MongoDB.com/ai Odoo https://Odoo.com/twist Today's show: AI models can solve PhD-level math equations and code...

  • 2026 / 7 / 29
    Banning Chinese robots isn't regulatory capture | E2318

    This Week In Startups is made possible by: Northwest Registered Agent- NorthwestRegisteredAgent.com/twist Odoo - Odoo.com/twist MongoDB - MongoDB.com/ai Today's show: The FCC's decision to ban Chinese...

  • 2026 / 7 / 27
    While other cultivated meat companies are collapsing, this one turned a profit | E2317

    This Week In Startups is made possible by: Every.io https://every.io MongoDB https://MongoDB.com/ai Agree https://agree.com Today's show: *Most lab-grown meat companies have already gone under. It's...

  • 2026 / 7 / 24
    Why quantum has been "10 years away" for 30 years | E2316

    This Week In Startups is made possible by: PayPal Open https://paypalopen.com DigitalOcean https://do.co/twist Rippling https://Rippling.ai/twist Today's show: *For three decades now, we've been told that...

  • 2026 / 7 / 22
    Why this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E2315

    This Week In Startups is made possible by: Sentry https://sentry.io/twist Agree https://agree.com Northwest Registered Agent https://northwestregisteredagent.com/twist Today's show: French ex-martial artist...

  • 2026 / 7 / 20
    The AI Securing Your Workforce Before a Mistake Ever Becomes a Breach | E2314

    This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Superhuman https://superhuman.com YSecurity https://YSecurity.io/TWIST Today's show: *Cybersecurity has long focused on cleaning...

  • 2026 / 7 / 20
    An AI that watches your every click may be the future of work | E2314

    This Week In Startups is made possible by: Vanta https://www.vanta.com/twist Superhuman https://superhuman.com YSecurity https://YSecurity.io/TWIST Today's show: *Cybersecurity has long focused on cleaning...

  • 2026 / 7 / 17
    The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313

    The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313 This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twist CLA...

  • 2026 / 7 / 15
    A Startup Is Trying to Buy PayPal… Craziest Deal of 2026! | E2312

    This Week In Startups is made possible by: MongoDB - MongoDB.com/ai Rippling - Rippling.ai/twist Agree.com - agree.com Today's show: Hustle Fund's Eric Bahn and Chapter One's Jeff Morris Jr. join our...

  • 2026 / 7 / 13
    Jason turned $11 and one tweet into 1.1M views | E2311

    This Week In Startups is made possible by: Quo https://quo.com/TWiST PayPal Open https://paypalopen.com Northwest Registered Agent https://northwestregisteredagent.com/twist Today's show: *Jason spent $11...

  • 2026 / 7 / 10
    Danny Bernstein left Big Tech to fund farm-bots | E2310

    This Week In Startups is made possible by: NetSuite https://NetSuite.ai/TWIST Squarespace https://squarespace.com/twist YSecurity https://YSecurity.io/TWIST Today's show: *America posted 400,000 farm jobs...

  • 2026 / 7 / 8
    Why Data Is the Next $1 Trillion Market

    This Week In Startups is made possible by: Digital Ocean - do.co/twist Agree.com - agree.com Every.io - every.io. Today's show: How many startups matter in tech? Fewer than you think. That's why venture...

  • 2026 / 7 / 6
    $100T is managed by “human duct tape” | E2308

    This Week In Startups is made possible by:Northwest Registered Agent https://northwestregisteredagent.com/twistVanta https://www.vanta.com/twistSentry https://sentry.io/twistToday’s show:*There are $100...

  • 2026 / 7 / 6
    $100T is managed by "human duct tape" | E2308

    This Week In Startups is made possible by: Northwest Registered Agent https://northwestregisteredagent.com/twist Vanta https://www.vanta.com/twist Sentry https://sentry.io/twist Today's show: *There are...

  • 2026 / 7 / 1
    Why the VC Hype Cycle Always Gets It Wrong | VC Roundtable | E2307

    This Week In Startups is made possible by:CLA - www.claconnect.com/withyouNorthwest Registered Agent - www.northwestregisteredagent.com/twistAgree.com - www.agree.comToday’s show:Forget the...

  • 2026 / 6 / 29
    Chamath on why young people need more agency, risk, and adventure

    This Week In Startups is made possible by:Plaudhttps://Plaud.ai/twistShopifyhttps://shopify.com/twistLinkedIn Jobshttps://LinkedIn.com/twistNorthwest Registered...

  • 2026 / 6 / 27
    Why F1 Teams are Replacing Wind Tunnels with Smart Tape | E2305

    This Week In Startups is made possible by:Plaud - https://Plaud.ai/twistSentry - https://sentry.io/twistNorthwest Registered Agent-https://northwestregisteredagent.com/twistDigitalOcean -...

  • 2026 / 6 / 24
    Why the Future of Video Games is Moving Back to the Dinner Table

    This Week In Startups is made possible by:Deel - deel.com/twistNorthwest Registered Agent - northwestregisteredagent.com/twistLinkedIn - linkedIn.com/twistToday’s show:Jason sits down with Brynn Putnam, CEO...

  • 2026 / 6 / 22
    The hottest running app has nothing to do with speed | E2303

    This Week In Startups is made possible by:Agree - https://agree.comQuo - https://quo.com/TWiSTSuperhuman - https://superhuman.comToday’s show:In this double-header, Jason and Lon chat with Louis Phillips,...

  • 2026 / 6 / 18
    Why SpaceX Buying Cursor Changes Everything

    This Week In Startups is made possible by:Deel - deel.com/twistLinkedIn - linkedIn.com/twistNorthwest Registered Agent - northwestregisteredagent.com/twistPlaud - https://Plaud.ai/twistToday’s show:Anthropic...

  • 2026 / 6 / 15
    The Startup Building the First Hotel on the Moon…

    This Week In Startups is made possible by:Every.io - visit every.ioSentry.io - sentry.io/twistVanta - vanta.com/twistToday’s show:The next SpaceX won't be building rockets; it'll build the first hotel...

  • 2026 / 6 / 13
    SpaceX IPO Day: What Wall St. and the media missed | E2300

    This Week In Startups is made possible by:Plaud https://Plaud.ai/twistPilot https://pilot.com/twistAgree https://agree.comIM8 Health https://IM8health.com/twistAfter watching Elon build out his rocket (and...

  • 2026 / 6 / 10
    Why the most expensive Seed deals are the cheapest | E2299

    This Week In Startups is made possible by:NetSuite - Netsuite.com/TWiSTDeel - Deel.com/TWiSTSquarespace - Squarespace.com/TWiSTTwo days before SpaceX launches the largest IPO in history at a flat $135/share,...

  • 2026 / 6 / 8
    The AI Tutor That Makes Kids Actually Think | E2298

    The AI Tutor That Makes Kids Actually Think | E2298This Week In Startups is made possible by:Northwest Registered Agent https://northwestregisteredagent.com/twistLinkedIn Jobs...

  • 2026 / 6 / 6
    Anthropic wants to slow AI down and Bernie wants 50%: JCal Reacts | E2297

    This Week In Startups is made possible by:Grasshopper Bank https://grasshopper.bank/twistVanta https://www.vanta.com/twistRender https://render.com/twistPlaud https://Plaud.ai/twistToday’s show:Anthropic...

  • 2026 / 6 / 3
    The Startup Turning Space Into a Logistics Network

    This Week In Startups is made possible by:Northwest Registered Agent - NorthwestRegistereAagent.com/TWISTEvery - Every.ioSentry - Sentry.io/TWISTToday’s show:Want to get to space? Several launch companies can...

  • 2026 / 6 / 3
    The project SpaceX's first employee raised $500M for

    This Week In Startups is made possible by:Northwest Registered Agent - NorthwestRegistereAagent.com/TWISTEvery - Every.ioSentry - Sentry.io/TWISTToday’s show:Want to get to space? Several launch companies can...

  • 2026 / 6 / 1
    This Startup Fused Human Brain Cells with Silicon Chips | E2295

    This Week In Startups is made possible by:Deel https://deel.com/twistQuo https://quo.com/TWiSTLinkedIn Jobs https://LinkedIn.com/twistToday’s show:Cortical Labs is the world’s first company selling biological...

  • 2026 / 5 / 29
    How to Raise a Seed Round in 2026: Ask Jason | E2294

    This Week In Startups is made possible by:partner 1 - linkpartner 2 - linkpartner 3 - linkToday’s show:Jason breaks down the real math behind raising a seed round. Here’s the funnel: contact 150 firms, get 50...

  • 2026 / 5 / 27
    The Drone Company Quietly Taking Over Delivery

    This Week In Startups is made possible by:Render - render.com/twistDeel - deel.com/twistNorthwest Registered Agent - northwestregisteredagent.com/twistToday’s show:The "Ryanair of drone delivery"...

  • 2026 / 5 / 23
    From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E2292

    This Week In Startups is made possible by:Every.io https://every.ioShopify https://shopify.com/twistRender https://render.com/twistPlaud https://Plaud.ai/twistToday’s show:Startups like Divergent Technologies...

  • 2026 / 5 / 20
    Avi Patel on the startup that copied Kled and why he called out General Catalyst by name | E2291

    This Week In Startups is made possible by:Grasshopper Bank - https://grasshopper.bank/twistLinkedIn - https://linkedIn.com/twistNorthwest Registered Agent - https://northwestregisteredagent.com/twistPlaud -...

  • 2026 / 5 / 18
    Why does Gen Z hate AI?

    This Week In Startups is made possible by:Vanta - Vanta.com/TWISTSentry - Sentry.io/TWISTDeel - Deel.com/TWISTToday’s show:AI is the villain of the 2026 commencement cycle, with business luminaries —...

  • 2026 / 5 / 18
    Why is Gen Z hates AI?

    This Week In Startups is made possible by:Vanta - Vanta.com/TWISTSentry - Sentry.io/TWISTDeel - Deel.com/TWISTToday’s show:AI is the villain of the 2026 commencement cycle, with business luminaries —...

  • 2026 / 5 / 15
    The Self-Driving Startup Nobody Saw Coming | E2289

    This Week In Startups is made possible by:IM8 Health: IM8health.com/TWISTSquarespace: Squarespace.com/TWISTRender - Render.com/TWISTSelf-driving just stopped being a science problem and became an engineering...

  • 2026 / 5 / 13
    How Many Startups Will Survive OpenAI? | E2288

    This Week In Startups is made possible by:Pilot -⁠ https://Pilot.com/TWIST⁠Grasshopper Bank -⁠ https://Grasshopper.bank/TWIST⁠Quo -⁠ https://Quo.com/TWiST⁠Plaud - ⁠https://Plaud.ai/twist⁠Anthropic just...

  • 2026 / 5 / 13
    How the 1% Will Own Compute (and What It Means for You)

    The future of AI isn't a smarter chatbot. It's a model that watches your screen, listens to the room, and acts on what it sees. We dug into Thinking Machines' new interaction model, what it means...

  • 2026 / 5 / 11
    Cerebras's IPO goes vertical, and the death of OpenClaw? | E2287

    Today’s show:Cerebras just jacked its IPO range to $150–$160 a share, OpenAI bought a consulting firm to seed its $4 billion private-equity joint venture, and a startup in Oakland is electrolyzing magnesium...

  • 2026 / 5 / 9
    5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286

    This Week In Startups is made possible by:IM8 Health - https://IM8health.com/TWISTEvery - Every.ioSentry - https://Sentry.io/TWISTBanks don’t want to hand over their data to AI labs. So David Moscatelli built...

  • 2026 / 5 / 6
    The end of Venture Capital? (VC Roundtable) | E2285

    This Week In Startups is made possible by:Grasshopper Bank - https://grasshopper.bank/twistPaperOS - https://paperos.com/twistLinkedIn Jobs - https://linkedIn.com/twistPlaud - https://Plaud.ai/twistThe top 5...

  • 2026 / 5 / 5
    Naval's GP, Ankur Nagpal, Breaks Down The Viral “USVC” Fund | E2284

    This Week In Startups is made possible by:Render - render.com/twistVanta - vanta.com/twistNorthwest Registered Agent - northwestregisteredagent.com/twistHave you wanted to invest in venture capital alongside...

  • 2026 / 5 / 5
    Naval's GP, Ankur Nagpal, Breaks Down The Viral "USVC" Fund | E2284

    This Week In Startups is made possible by: Render - render.com/twist Vanta - vanta.com/twist Northwest Registered Agent - northwestregisteredagent.com/twist Have you wanted to invest in venture capital...

  • 2026 / 5 / 1
    Can an AI Agent Legally Own a Company? Christian van der Henst's Wild Experiment| E2283

    This Week In Startups is made possible by:Pilot - https://pilot.com/twistShopify - https://shopify.com/twistGrasshopper Bank - https://grasshopper.bank/twistToday’s show:An AI agent named Valerie is running a...

  • 2026 / 4 / 30
    Mastering AI Video Marketing w/ Magnific CEO JoaquĂ­n Cuenca Abela | AI Basics

    The TWiST AI Basics series is made possible by Google Cloud!Check out Google Cloud’s new report, “Future of AI: Perspectives on generative media for startups,” Featuring thoughts from today’s guest, Joaquín...

  • 2026 / 4 / 29
    The $10M+ Bet on a Beanie That Reads Your Brain | Sabi & the Future of BCI | E2282

    This Week In Startups is made possible by:Render - https://Render.com/TWISTNorthwest Registered Agent - https://NorthwestRegisteredAgent.com/TWISTLinkedIn Jobs - https://LinkedIn.com/TWISTToday’s show:A...

  • 2026 / 4 / 28
    To the left of this of thumbnail i want to add a chinese flag to the left destroying the meta logo. because the title is China Kills Meta / Manus Deal (Story Of The Year) | E2281

    This Week In Startups is made possible by:IM8 Health - IM8health.com/twistSentry - Sentry.io/twistDeel - Deel.com/twistPlaud - https://Plaud.ai/twistWhat’s the technology story of the year? No, it’s not...

  • 2026 / 4 / 28
    China Kills Meta / Manus Deal (Story Of The Year) | E2281

    This Week In Startups is made possible by:IM8 Health - IM8health.com/twistSentry - Sentry.io/twistDeel - Deel.com/twistPlaud - https://Plaud.ai/twistWhat’s the technology story of the year? No, it’s not...

  • 2026 / 4 / 25
    Naval’s $500 VC fund, the Maduro Polymarket scandal, and NYT defends theft and murder | E2280

    This Week In Startups is made possible by:Northwest Registered Agent - https://northwestregisteredagent.com/twist LinkedIn Jobs - https://LinkedIn.com/twistToday’s show:It’s a News and Off-Duty weekend...

  • 2026 / 4 / 25
    Naval's $500 VC fund, the Maduro Polymarket scandal, and NYT defends theft and murder | E2280

    This Week In Startups is made possible by: Northwest Registered Agent - https://northwestregisteredagent.com/twist LinkedIn Jobs - https://LinkedIn.com/twist Today's show: It's a News and Off-Duty weekend...