Description
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
Episodes
- 2025 / 5 / 30How AthenaHQ and Browser Use Are Building the Next Layer of the Internet | E2132Today’s show: Alex interviews two cutting-edge startups shaping the future of AI: AthenaHQ, pioneering “GEO” (Generative Engine Optimization) to help brands rank in AI-powered search engines like ChatGPT and...
- 2025 / 5 / 28Google’s AI Design Tool, Salesforce’s $8B Comeback Deal, and M&A Momentum Builds | E2131In this episode, we cover three major stories shaping the startup and tech landscape. First, Google unveils Stitch, an AI-powered web design tool with one-click export to Figma—signaling a major disruption...
- 2025 / 5 / 23Apple’s Tariff Trouble, Anthropic’s New Models, and Our Founder Friday Finale | E2130Today’s show: Trump takes aim at Apple with a potential 25% iPhone tariff, Anthropic releases two powerful new Claude models claiming top performance in coding tasks, and two founders go head-to-head in the...
- 2025 / 5 / 22David Friedberg on AI-First Startups & the Future of Biology, Business & Creativity | AI Basics with Google CloudIn this episode, Jason chats with David Friedberg—CEO of Ohalo Genetics and co-host of the All-In Podcast—about how AI is transforming agriculture and startups. David introduces Ohalo’s "Boosted Breeding"...
- 2025 / 5 / 21Jony Ive Joins OpenAI, Waymo Hits 10M Rides, and How to Launch a Marketplace from Scratch | E2129Today’s show: Jason and Alex dicsuss Jony Ive's $6.5B deal with OpenAI and what it means for the future of AI hardware, Tesla’s push into robotaxis vs. Waymo’s 10M paid rides, and Microsoft’s latest move...
- 2025 / 5 / 20Drones, Design, and Digital Espionage | E2128Today’s show: Jason and Lon explore the wild edges of tech innovation and regulation — from a student-built acoustic weapon that takes down drones (without harming humans) to the legal gray areas of drone...
- 2025 / 5 / 16Microsoft Layoffs, Immigration Blunders, & Office Hours with Jeremy Redman of Airfive | E2127Today’s show: Microsoft lays off 6,000 employees despite record profits, signaling a ruthless new phase in big tech. Jason, Lon, and Alex discuss what it means for the talent market, why tightening U.S....
- 2025 / 5 / 15Chime’s IPO, Databricks’ $1B Acquisition & Dave Rubin’s Media Empire | E2126Today’s show: Chime is finally going public with strong financials and a shot at matching its $25B 2021 valuation, signaling real momentum in the IPO market. Databricks just made a $1B bet on agentic AI by...
- 2025 / 5 / 13Agentic AI Meets Cybersecurity + Solar Robots in the Desert | E2125Today’s show: Alex interviews founders from two frontier technologies reshaping our world. First, ZioSec is tackling the cybersecurity risks of AI agents with continuous adversarial testing before real...
- 2025 / 5 / 13Anti-Work Uprising, Copyright Wars & the StreamFog Solution | E2124Today’s show: Jason, Lon & Alex are back with a spicy Monday episode of This Week in Startups. Jason goes off on unions vs capitalism, we dig into why fewer seed startups are making it to Series A, and look...
- 2025 / 5 / 10OpenAI Scoops Instacart’s CEO, AI in the Courtroom & Off-Road Startups | E2123Today’s show: Jason, Alex, and Lon break down OpenAI’s latest power move: hiring Instacart CEO Fidji Simo to lead its consumer apps. They also dive into the ethical storm brewing around an AI-generated victim...
- 2025 / 5 / 8Zoox Crash Fallout, COATUE’s $1B Open Fund, and Office Hours with FusionAds | E2122Today’s show: Jason, Lon & Alex discuss the day’s hottest tech and startup news. Zoox’s robotaxi crash and voluntary recall, COATUE’s innovative open-ended venture fund that could democratize private tech...
- 2025 / 5 / 6Cursor’s $9B Round, AI-Powered Toys & CloudNuro’s SaaS Fix | E2121Today’s show: Cursor’s explosive growth, hitting $200M in ARR and a massive $9B valuation. They also explore the buzz around Magical Toys’ new AI-powered dinosaur, where LLMs meet playtime. The conversation...
- 2025 / 5 / 2Apple’s App Store Loss, AI Persuasion, and an Interview with Tyler Denk of Beehiiv | E2120Today’s show: Jason, Lon, and Alex break down a loaded week in tech: Apple’s 27% App Store “link-out” fee gets shut down by a judge—unlocking margin for startups and slashing CAC; AI bots on Reddit’s...
- 2025 / 5 / 1What's Next for AI Infrastructure with Amin Vahdat | AI Basics with Google CloudIn this episode of AI Basics, Jason sits down with Amin Vahdat, VP of ML at Google Cloud, to unpack the mind-blowing infrastructure behind modern AI. They dive into how Google’s TPUs power massive queries,...
- 2025 / 5 / 1Bittensor’s Rise, Meta’s Llama Goes Cloud, & AI Now Writes Your Code | E2119Today’s show: Jason, Alex, Lon and Special Guest Mark Jeffrey of Hash Rate, cover the explosive rise of Bittensor, a decentralized AI compute network some are calling the “third great coin” after Bitcoin and...
- 2025 / 4 / 29Meta’s Dangerous Chat, Protect AI & Founder Fridays Pitch Comp | E2118Today’s show: we break down the wild story behind Meta’s AI chatbots going completely off the rails — including a bombshell WSJ exposé about bots flirting with minors. Then they cover Palo Alto Networks’ huge...
- 2025 / 4 / 25Discord’s Power Move, Slate’s Modular EVs & the “Act for Private Gain” | E2117Today’s show: Jason, Alex, and Lon break down today’s top tech and startup stories — from Slate Auto’s customizable $25K EV truck to Discord’s major leadership shakeup ahead of a potential IPO. They also...
- 2025 / 4 / 23Cursor’s $300M ARR, Uber’s FTC Battle, and Office Hours with GoShare | E2116Today’s show: Jason, Alex and Lon unpack the FTC’s lawsuit against Uber and what it could mean for subscription UX, break down how AI startup Cursor is growing faster than almost any SaaS company in history,...
- 2025 / 4 / 21Robot Lifeguards, TapCheck’s Payday Play & Thalamus’s Wild Market Share | E2115Today’s show: Jason and Lon break down the biggest stories in tech and startups this week: OpenAI’s new models are powerful but glitchy, Meta’s internal docs hint that Zuck knows the Facebook friends graph is...
- 2025 / 4 / 18LMArena Goes Startup, AI App Wars Begin, Scott Bair’s Design Playbook | E2114Today’s show: Jason, Alex, and Lon discuss the rise of LMArena as it spins out into a full-fledged startup, what that means for AI benchmarking, and how it could monetize its growing community. They also dive...
- 2025 / 4 / 17AI Progress and Impact on Ecosystem Players with CapitalG’s Jill Chase | AI Basics with Google CloudIn this episode of AI Basics, Jason sits down with CapitalG partner Jill Chase to break down how AI is reshaping the startup ecosystem — from founders to investors to incumbents. They cover how CapitalG...
- 2025 / 4 / 17Cuts CEO Talks Tariffs, Figma's IPO Buzz, and a Nerd Crawler Update | E2113Today’s show: Jason, Alex, and Lon discuss Figma’s surprise IPO filing following its $1B breakup from Adobe, OpenAI’s quiet push into social networking through a Sora image-sharing feed, and how sweeping new...
- 2025 / 4 / 15Vertical AI Innovations: Abacus LLM in Finance & Synthesia's Video Avatars | E2112Today’s show: Alex interviews founders from Abacus and Synthesia—two companies leading the charge in vertical AI. Abacus is deploying on-prem LLMs to banks and insurers with a focus on data control, accuracy,...
- 2025 / 4 / 15HuggingFace Buys Pollen Robotics, DHH & Bezos Founder Advice & a JCal Origin Story | E2111Today’s show: In this episode, Jason, Alex, and Lon dive into Blue Origin’s all-female celeb spaceflight (yes, Katy Perry sang on reentry), Hugging Face’s unexpected move into robotics, and Jack Dorsey’s wild...
- 2025 / 4 / 12Palantir's Fellowship, Coco Robots & Startup Office Hours | E2110Today’s show: We dive into the latest tech and startup news — including Palantir’s bold new fellowship program that challenges the traditional college path, and DoorDash’s rollout of burrito-delivering Coco...
- 2025 / 4 / 1070mph Drone Deliveries, 125% Tariffs & What $10M Exits Really Mean | E2109Today’s show: Jason, Alex, and Lon talk about stories reshaping the startup world: 70mph drone deliveries are officially live in Dallas, with Zipline and Walmart promising groceries “as the crow flies” in...
- 2025 / 4 / 8Economic Chaos, More Pitch Madness & the Shopify AI Manifesto | E2108Today’s show: Jason and Alex unpack a wild week in tech and the markets — including a fake tweet that moved $4 trillion and Trump’s latest tariff talk. Lon jumps in for another round of Founder Fridays Pitch...
- 2025 / 4 / 5Rippling Targets $16B, Market Chaos, TikTok Timeout, and Office Hours | E2107Today’s show: Jason and Alex dive into the startup world’s latest chaos — from Nasdaq’s slide and Trump’s tariffs to Klarna’s IPO pause and Rippling’s $16B target. They break down what founders really need to...
- 2025 / 4 / 3Spycraft in SaaS, Rabbit’s Comeback, and Startup Pitch Madness | E2106This Week in Startups is brought to you by…Kyte - TWIST Listeners: Go to https://kyte.com/ and download the Kyte app today. Use code JASON to save 10% on your first rental.Atlassian - Head to...
- 2025 / 4 / 1M&A Mania, Palantir Meme Crash + Office Hours with Hookhub | E2105Today’s show: Circle gears up for its IPO and the stablecoin wars heat up, Palantir’s meme stock status gets a reality check, and they riff on a possible Uber + DoorDash merger and whether AI should train on...
- 2025 / 3 / 29AI Revolution Gains, Non-Consensus Startups & Prosperous AI | E2104Today’s show: Jason, Alex, and Lon cover everything from wild political headlines to big moves in AI and venture. They kick things off with the surprising Trump pardon of Trevor Milton, the disgraced Nikola...
- 2025 / 3 / 2711x in Trouble and China's AI Acceleration | E2103OpenPhone - Streamline and scale your customer communications with OpenPhone. Get 20% off your first 6 months at www.openphone.com/twistLinkedIn Ads - To redeem a $100 LinkedIn ad credit and launch your first...
- 2025 / 3 / 2523andMe BANKRUPT, Saylor Still Buying Bitcoin, + Founder Interviews | E2102Today’s show: In this episode, Alex and Lon kick things off with the latest tech news — including 23andMe’s dramatic collapse, MicroStrategy’s half-million Bitcoin haul, and whether we’re finally seeing a...
- 2025 / 3 / 21Fact-Checking Mark Rober, and the Fall of TechCrunch | E2101Today’s show: Jason, Alex, and Lon break down a subreddit question: A founder builds 100% of the product, is promised equity—and now he’s being pushed out. We break down exactly what he should do next. Plus,...
- 2025 / 3 / 19Tesla vs. Mark Rober, Google’s $32B M&A Bet, & XRP’s SEC Victory | E2100Today’s show: Tesla FSD drama, Google’s massive $32B cybersecurity bet, and XRP’s SEC victory. Jason, Lon, and Alex break down the internet firestorm over Mark Rober’s viral Tesla test, why Google’s Wiz...
- 2025 / 3 / 18AI-Powered Coding & Space Tugboats? Inside the Future of Software & Satellites! | E2099Today’s show: Alex interviews two incredible founders from the TWIST 500! First, Replit CEO Amjad Masad breaks down how AI-powered coding is changing software development and what the future of agents looks...
- 2025 / 3 / 17Self-Driving Car Myths, Klarna’s Big IPO & Netflix’s $300M Gamble | E2098Today’s show: Jason, Alex, and Lon break down a wild viral test on self-driving cars— will FSD see through fog, or does LiDAR win? Plus, Klarna is finally going public… but is "buy now, pay later" still the...
- 2025 / 3 / 14Europe’s Startup Future with Harry Stebbings | E2097This Week in Startups is brought to you by…Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistSquarespace - Use offer code TWIST to save 10% off your first purchase of a...
- 2025 / 3 / 13Is Project Europe a YC Riff? Nick Denton is Back! And more! | E2096Today’s show: Europe wants to keep its founders from fleeing, AI is growing at breakneck speed, and Nick Denton is back with a spicy Twitter storm—so we had to talk about it. Jason, Alex, and Lon break down...
- 2025 / 3 / 11The Future of AI Customer Support with LiveX AI’s Jia Li | AI Basics with Google CloudIn this episode of AI Basics, Jason sits down with Jia Li from LiveX AI to explore how human-like AI agents are changing the game for businesses. Instead of clunky bots, these AI agents engage customers in...
- 2025 / 3 / 11Student Roy Lee Hacks Amazon, SBF's Jailhouse Chat + more! | E2095Timestamps:(0:00) Roy Lee's hack and Amazon's reaction(3:03) MicroStrategy's Bitcoin strategy(4:29) Market reactions to Trump's policies(6:33) Creating value in current market conditions(8:00) South by...
- 2025 / 3 / 7AI’s Next Leap: Hyper-Realistic Agents & Unlimited Power | E2094Today’s show: AI is evolving at lightning speed—smarter assistants, faster models, and now, the massive energy demands that come with it. In this episode, Alex dives into two cutting-edge companies from the...
- 2025 / 3 / 5Coreweave IPO, AVRide & Digg is Back! | E2093This Week in Startups is brought to you by…Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit...
- 2025 / 3 / 4AI Agents & the Future of Work with LangChain’s Harrison Chase | AI Basics with Google CloudIn this episode: Jason sits down with Harrison Chase, CEO of LangChain, to explore how AI-powered agents are transforming the way startups operate. They discuss the shift from traditional entry-level roles to...
- 2025 / 3 / 4US Crypto Reserve Bombshell, Ramp’s $13B Climb, & more | E2092Today’s show: Trump just floated the idea of a U.S. Crypto Reserve, suggesting a 10 bips transaction tax and naming unexpected altcoins like XRP, Solana, and Cardano. Jason and Alex break down what this means...
- 2025 / 3 / 1Board Talk Empire with GRIN's Brandon Brown, Founder Hacks & SEC Memecoin Clarity? | E2091Today’s show: Jason and Alex break down the latest head-scratching SEC ruling on meme coins—did they just legalize pump-and-dumps to protect Trump’s token? Plus, they dive into why venture debt can destroy...
- 2025 / 2 / 27The Incredible Double Interview: Superhuman and Robinhood | E2090This Week in Startups is brought to you by…Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistNorthwest Registered Agent. Get more privacy, more options, and more done—visit...
- 2025 / 2 / 27The Incredible Double Interview: Superhuman and RobinhoodThis Week in Startups is brought to you by…Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistNorthwest Registered Agent. Get more privacy, more options, and more done—visit...
- 2025 / 2 / 25Apple Drops $500B on AI while Google Gemini Eyes Your iOS Devices! | E2089Today’s show: Jason and Lon break down the latest trends shaping AI training, the evolving job market, and the shifting landscape of social media. A tribute to Steve Jobs on what would have been his 70th...